About microGENOMICS
Background
Background
Background
microGENOMICS is a platform curated by Dr. Vikas Sharma, a bioinformatician specialising in genomics and Next-Generation Sequencing (NGS). Designed as a nexus for genomic enthusiasts, the website offers insightful research highlights, advanced bioinformatics tools, and a collaborative space for the genomics community. Dive into the micro
microGENOMICS is a platform curated by Dr. Vikas Sharma, a bioinformatician specialising in genomics and Next-Generation Sequencing (NGS). Designed as a nexus for genomic enthusiasts, the website offers insightful research highlights, advanced bioinformatics tools, and a collaborative space for the genomics community. Dive into the microscopic world of genomes with Dr. Sharma and discover the potential that lies within.
Skills
Background
Background
Dr. Vikas Sharma has carved a niche for himself in genomics and Next-Generation Sequencing (NGS). His adeptness in the technical intricacies of high-throughput sequencing has propelled several groundbreaking research endeavors. Dr. Sharma's mastery in genomic data analysis is further underscored by his proficiency in Python and R programm
Dr. Vikas Sharma has carved a niche for himself in genomics and Next-Generation Sequencing (NGS). His adeptness in the technical intricacies of high-throughput sequencing has propelled several groundbreaking research endeavors. Dr. Sharma's mastery in genomic data analysis is further underscored by his proficiency in Python and R programming, essential tools for statistical analysis in genomics. Beyond the conventional techniques, Dr. Sharma has delved deep into machine learning and data science, optimizing their applications for nuanced genomic data interpretation. Each technique and skill he's honed is a testament to his relentless pursuit of excellence in the microscopic world of genomics.
Education
Background
Education
Dr. Vikas Sharma boasts a formidable academic foundation in genomics and bioinformatics, underscoring his prowess in these intricate domains. He earned his Ph.D. in Bioinformatics and Genomics with a specialization in Next-generation Sequencing (NGS) Data Analysis from the esteemed Indian Institute of Technology Mandi between 2013 and 201
Dr. Vikas Sharma boasts a formidable academic foundation in genomics and bioinformatics, underscoring his prowess in these intricate domains. He earned his Ph.D. in Bioinformatics and Genomics with a specialization in Next-generation Sequencing (NGS) Data Analysis from the esteemed Indian Institute of Technology Mandi between 2013 and 2019. Prior to this, Dr. Sharma undertook an integrated B.Tech. – M.Tech. program in Biotechnology at Lovely Professional University (LPU) from 2007 to 2012. Situated in Phagwara, Punjab, LPU provided the initial impetus to his journey, which was further honed and refined at IIT Mandi in Himachal Pradesh.
Publications
Anaerobic Co-digestion of Food Waste, Bio-flocculated Sewage sludge, and Cow Dung in CSTR using E_C2(Tx) Synthetic Consortia
Thakur H#, Rashmi#, Verma N, Sharma V, Kumar S, Powar S, Prakash T$, Dhar A$, Environ. Technol. Innov., 32, 103263 | 2023
Microbial cell-free DNA detection: non-invasive diagnosis of infectious diseases
Kanaujia R#, Sharma V#, Biswal M, Singh S, Ray P, Angrup A, Indian J. Med. Microbiol., 46, 100433| 2023
Can beta-lactamase resistance genes in anaerobic Gram-negative gut bacteria transfer to gut aerobes?
Sood A, Sharma V, Angrup A, Ray P, J. Antibiot. (Nature Publishing Group), DOI: 10.1038/s41429-023-00608-z| 2023
Direct diagnosis of scrub typhus by full-length 16S rRNA gene analysis using Oxford Nanopore sequencing
Sharda SC, Bisht K,Sharma V, Lakku PR, Bhatia MS, Sharma N, Biswal M, Int. J. Infect. Dis., DOI:10.1016/j.ijid.2022.10.040| 2022
Comparative genomics reveals the evolution of antimicrobial resistance in Bacteroides nordii
Sharma V, Sood A, Ray P, Angrup A, Microb. Pathog., 105811| 2022
Colonization of the central venous catheter by Stenotrophomonas maltophilia in an ICU setting: an impending outbreak managed in time
Kanaujia R, Bandyopadhyay A, Biswal M, Sahni N, Kaur K, Vig SS, harma V, Angrup A, Yaddanapudi LN, Ray P, Am. J. Infect. Control, S0196 -6553(21)00709-4 | 2022
In silico functional and evolutionary analyses of the rubber oxygenases (RoxA and RoxB).
Sharma V, Mobeen F, Prakash T, 3 Biotech, 10, 376 | 2020
Comparative human gut microbiome analysis of Prakriti and Sasang Systems reveals functional level similarities in the constitutionally similar classes.
Mobeen F, Sharma V, Prakash T , 3 Biotech, 10, 379 | 2020
Functional signature analysis of extreme Prakriti endo-phenotypes in gut microbiome of western Indian rural population.
Mobeen F, Sharma V, Prakash T, Bioinformation, 15, 490-505 | 2019
Exploration of survival-traits, probiotic-determinants, host-interactions, and functional evolution of bifidobacterial genomes using comparative genomics.
Sharma V, Mobeen F, Prakash T, Genes 9 (10), 477| 2018
Enterotype variations of the healthy human gut microbiome in different geographical regions.
Mobeen F, Sharma V, Prakash T , Bioinformation, 14, 560-573 | 2018
Metabolic and taxonomic insights into the Gram-negative natural rubber degrading bacterium Steroidobacter cummioxidans sp. nov., strain 35Y.
Sharma V, Siedenburg G, Birke J, Jendrossek D, Mobeen F, Prakash T, PloS One 13(5), e0197448 | 2018
Western Indian rural gut microbial diversity in extreme Prakriti endo-phenotypes reveals signature species.
Chuahan NS,Pandey R,Mondal AK,GuptaS,KumarJ,PatilR,Agarwal D,Girase B,Shrivastava A,Mobeen F,Sharma V,Prakash T,Juveka RS, Prasher B, Mukerji M, Dash D, Front. Microbiol., 9 (2018): 118| 2018
Characterization of Phormidium lacuna strains from the North Sea and the Mediterranean Sea for biotechnological applications.
Nies F, Worner S, Wunsch N, Armant O,Sharma V, Hesselschwerdt, A, Falk F, Weber, N, Weiß J, Trautmann A, Posten C, Prakash T, Lamparter T, Process Biochem., 59, 194-206 | 2017
Comparative genomics of Herpesviridae family to look for potential signatures of human infecting strains.
Sharma V, Mobeen F, Prakash T, Int. J. Genomics, 2016, 9543274| 2016
Functional assignment of metagenomic data: insights for the microbial nitrogen cycle in Metagenomics of the microbial nitrogen cycle: theory, methods and applications.
Sharma V, Chetal G, Taylor TD, Prakash T, Ed: Diana Marco. Pub: Caister Academic Press, United Kingdom.Page(s): 268. ISBN 978-1-9 08230-48-5. | September, 2014
Potential cellulase production, optimization and saccharification study by novel thermophilic microbes.
Sharma V, Vij H, Singh PK, Bhatt SM, ABS J. Sustain. Biotech. 1, 19-26 | 2013
Strain Improvement of Bacillus coagulans and Geobacillus stearothermophilus for enhanced thermostable cellulase production and the effect of different metal ions on cellulase activity.
Sharma V, Singh PK, Int. J. Eng. Sci. Technol., 4(11), 4704-4709 | 2012
Nanotechnology: an emerging future trend in wastewater treatment with its innovative products and processes.
Sharma V, Sharma A, Int. J. Enhanc. Res. Sci. Technol. Eng. 1, 121-128 | 2012
The genomics of the emerging pathogen Gemella haemolysans: Novel insights into antimicrobial resistance, pathogenicity, and genome evolution
Sharma V#, Verma S#, Kaur M#, Tekchandani U, Angrup A, Singh SR, Gupta V, Under Review (Microbes and Infection)
Microbial community dynamics by metagenomic profiling of synthetically designed microbial consortia for biohythane production using raw “Cow Dung” as substrate
Rashmi#, Sharma V, Kumar S, Prakash T, Under Review (Biodegradation)
Identification of resistome,mobilome,and horizontal genomics in multidrug-resistant Bacteroides fragilis:an in- vitro and in-silico study
Sood A#, Sharma V, Angrup A, Ray P, Under Review (International Journal of Antimicrobial Agents)
Microbial dynamics during anaerobic digestion of raw and electoflocullated waste water for biohythane production
Rashmi, Sharma V, Kumar S, Kaul M, Prakash T, In preparation
Synthetic microbial consortia designing using metagenomics approach for biohythane production
Rashmi, Sharma V, Kumar S, Kaul M, Sharma L, Halder A, Prakash T, In preparation
Comparative genomics of extraintestinal pathogenic Escherichia coli to explore the relationship of resistome , mobilome, and virulome with carbapenem- and colistin-resistance
Sharma V#, Verma S#, Angrup A, Biswal M, Arora A, Ray P, In preparation
# means equal first-co author contribution, $ means equal corresponding author contribution
Projects
Understanding the impact of gut microbiome dysbiosis and metabolic alterations in the pathogenesis (EOCRC) Colorectal Cancer (CRC)
Funding Agency: All India Institute of Medical Sciences (AIIMS), New Delhi| 2022
Role: Co-investigator.
PI: Dr Jyoti Sharma, AIIMS New Delhi
Co-I: Dr Subhradip Karmakar, Dr. Sandeep Bhoriwal, Dr. Rajni Yadav, AIIMS New Delhi
